Synthesis, characterization and antibacterial activity of new salicylhydrazide containing azopyrazoles

Bhupendra P. Patel, Hasmukh S. Patel, Purvesh J. Shah

Abstract


Various ethyl-2-substituted phenyl hydrazono-3-oxobutyrate (2a-h) condensation with 2-hydroxy benzoic acid hydrazide (3) to afford 1-(2-hydroxybenzoyl)-3-methyl-4-(2- substituted phenyl hydrazono)-1H-pyrazol-5(4H)-one (4a-h). The structures of all these compounds (4a-h) were recognized on basis of analytical and spectral data. The newly synthesized compounds were evaluated for their antimicrobial activity against various bacteria and fungi.

Keywords


pyrazoline-5-one; salicylhydrazide; antimicrobial activity; spectral studies

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Orbital: The Electronic Journal of Chemistry (e-ISSN 1984-6428) is a quarterly scientific journal published by the Institute of Chemistry of the Universidade Federal de Mato Grosso do Sul, Brazil. Orbital is a peer-reviewed, open-access journal.